Warner-Lambert/Parke-Davis Award lecture. Many tumors and many genes: genetics of uterine leiomyomata.
作者信息
Morton C C
机构信息
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
出版信息
Am J Pathol. 1998 Oct;153(4):1015-20. doi: 10.1016/s0002-9440(10)65645-3.
Abstract
摘要
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Cytogenetic abnormalities in uterine myomas are associated with myoma size.
Mol Hum Reprod. 1998 Jan;4(1):83-6. doi: 10.1093/molehr/4.1.83.
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Variation in the incidence of uterine leiomyoma among premenopausal women by age and race.绝经前女性子宫平滑肌瘤发病率随年龄和种族的变化。
Obstet Gynecol. 1997 Dec;90(6):967-73. doi: 10.1016/s0029-7844(97)00534-6.
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The del(7q) subgroup in uterine leiomyomata: genetic and biologic characteristics. Further evidence for the secondary nature of cytogenetic abnormalities in the pathobiology of uterine leiomyomata.子宫平滑肌瘤中的del(7q)亚组：遗传和生物学特征。子宫平滑肌瘤病理生物学中细胞遗传学异常继发性本质的进一步证据。
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Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search.全基因组搜索提示1号染色体上存在前列腺癌的主要易感基因座。
Science. 1996 Nov 22;274(5291):1371-4. doi: 10.1126/science.274.5291.1371.
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Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomas.子宫平滑肌瘤中HMGIC基因上游的易位断点表明，该基因的失调机制与脂肪瘤不同。
Genes Chromosomes Cancer. 1996 Sep;17(1):1-6. doi: 10.1002/(SICI)1098-2264(199609)17:1<1::AID-GCC1>3.0.CO;2-0.
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Genomic characterization of human HMGIC, a member of the accessory transcription factor family found at translocation breakpoints in lipomas.人类HMGIC的基因组特征分析，HMGIC是在脂肪瘤的易位断点处发现的辅助转录因子家族的一员。
Genomics. 1996 Jan 15;31(2):207-14. doi: 10.1006/geno.1996.0033.
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Cell. 1993 Sep 10;74(5):887-98. doi: 10.1016/0092-8674(93)90468-6.
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