Agroyannis B, Kalogirou D, Vitoratos N, Tzanatos H, Konstandinidou I, Koutsikos D, Zourlas P A
2nd Department of Obstetrics- Gynecology, Medical School, Aretaieon Hospital, University of Athens.
Clin Exp Obstet Gynecol. 1993;20(2):70-5.
Serum changes of Ferroxidase I and II well as the total iron binding capacity (TIBC) and unsaturated iron binding capacity (UIBC) were measured throughout their gestation in 32 normal pregnant women. Significantly higher concentrations for all the above mentioned parameters were found as pregnancy advanced. Moreover, a significant and positive correlation between the weeks of gestation and a) serum Ferroxidase I (r:0.568 p < 0.001), d) serum Ferroxidase II (r:0.619 p < 0.001), c) serum TIBC (r:0.549 p < 0.01), and d) serum UIBC (r:0.424 p < 0.05) was found. The parallel serum changes of both ferroxidase with those of TIBC and UIBC are also shown in this study. The correlation of Ferroxidase I with TIBC (r:0.734 p < 0.001) and UIBC (r:0.536 p < 0.01) as that of Ferroxidase II with TIBC(r:0.634 p < 0.001) and UIBC (r:0.513 p < 0.01) was significant and positive. In conclusion, serum Ferroxidase I and II are progressively increased with serum TIBC and UIBC as pregnancy advances.
对32名正常孕妇在整个孕期测定了血清铁氧化酶I和II、总铁结合力（TIBC）以及不饱和铁结合力（UIBC）。随着孕期进展，上述所有参数的浓度均显著升高。此外，发现妊娠周数与a）血清铁氧化酶I（r：0.568，p<0.001）、d）血清铁氧化酶II（r：0.619，p<0.001）、c）血清TIBC（r：0.549，p<0.01）和d）血清UIBC（r：0.424，p<0.05）之间存在显著正相关。本研究还显示了两种铁氧化酶与TIBC和UIBC的血清变化平行。铁氧化酶I与TIBC（r：0.734，p<0.001）和UIBC（r：0.536，p<0.01）的相关性以及铁氧化酶II与TIBC（r：0.634，p<0.001）和UIBC（r：0.513，p<0.01）的相关性均显著为正。总之，随着孕期进展，血清铁氧化酶I和II随血清TIBC和UIBC逐渐升高。
