Salomatin V V, Liutov A G, Enikeeva S A, Charnaia L F, Zurochka A V, Dolgushin I I
Vopr Med Khim. 1993 May-Jun;39(3):24-6.
Induced chemoluminescence of neutrophils was distinctly inhibited both in intact mice and the animals with thermal injury after administration of acid alpha 1-glycoprotein. At the same time, the glycoprotein decreased the rate of thermal burn-induced activation of lipid peroxidation in rat blood, skin and liver tissue. Antioxidative and therapeutic effects of acid alpha 1-glycoprotein in burns appear to be related to regulation of neutrophil activity.
给予酸性α1-糖蛋白后，完整小鼠和热损伤动物中性粒细胞的诱导化学发光均受到明显抑制。同时，该糖蛋白降低了大鼠血液、皮肤和肝脏组织中热烧伤诱导的脂质过氧化激活率。酸性α1-糖蛋白在烧伤中的抗氧化和治疗作用似乎与中性粒细胞活性的调节有关。
