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[胸腺激素新合成片段对淋巴细胞增殖反应的影响]

[The effect of new synthetic fragments of thymus hormones on the proliferative response of lymphocytes].

作者信息

Ivanova V P, Sorochinskaia E I, Lozhkina T K

出版信息

Vopr Med Khim. 1993 May-Jun;39(3):45-7.

PMID:8333191
Abstract

Influence of three new artificial fragments of beta-thymosines Phe-Asp-Lys-Ala, Glu-Lys-Phe-Asp-Lys and Thr-Leu-Pro-Thr on phytohemagglutinin-induced proliferative response of human lymphocytes was studied. These peptides studied either stimulated or inhibited incorporation of 3H-thymidine in cell cultures of human lymphocytes. Possible mechanisms of these effects of the peptides on lymphocyte proliferation are discussed.

摘要

研究了三种新型β-胸腺素人工片段Phe-Asp-Lys-Ala、Glu-Lys-Phe-Asp-Lys和Thr-Leu-Pro-Thr对植物血凝素诱导的人淋巴细胞增殖反应的影响。所研究的这些肽在人淋巴细胞细胞培养物中既刺激也抑制3H-胸腺嘧啶核苷的掺入。讨论了这些肽对淋巴细胞增殖产生这些作用的可能机制。

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