Seth H K, Frohnsdorff K G
J Am Geriatr Soc. 1977 Feb;25(2):94-5. doi: 10.1111/j.1532-5415.1977.tb00238.x.
A case of acquired hemophilia is presented. Widespread blisters and then ecchymoses developed in a 79-year-old woman who was severely demented. Laboratory studies revealed specific complete inhibition of factor VIII in the blood. In any elderly patient with a bleeding diathesis and an abnormality in intrinsic coagulation, the presence of inhibitors to factor VIII should be suspected.
本文报告1例获得性血友病。一名79岁重度痴呆女性身上出现广泛水疱,随后出现瘀斑。实验室检查显示血液中凝血因子VIII受到特异性完全抑制。对于任何有出血倾向且内源性凝血异常的老年患者,应怀疑存在凝血因子VIII抑制剂。