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发作间期癫痫灶活动的脑磁图定位及立体定向放射外科治疗。一种针对局灶性癫痫患者的非侵入性方法。

MEG localization of interictal epileptic focal activity and concomitant stereotactic radiosurgery. A non-invasive approach for patients with focal epilepsy.

作者信息

Hellstrand E, Abraham-Fuchs K, Jernberg B, Kihlström L, Knutsson E, Lindquist C, Schneider S, Wirth A

机构信息

Department of Clinical Neurophysiology, Karolinska Hospital, Stockholm, Sweden.

出版信息

Physiol Meas. 1993 May;14(2):131-6. doi: 10.1088/0967-3334/14/2/004.

DOI:10.1088/0967-3334/14/2/004
PMID:8334408
Abstract

Two patients with complex partial epilepsy and tumour of the temporal lobe scheduled for gamma knife radiosurgery were evaluated pre- and postoperatively by multichannel magnetoencephalography (MEG). Centers of epileptic dipole activity found preoperatively disappeared after the focal irradiation as did the epileptic seizures. Thus, to combine stereotactic MEG and gamma knife radiosurgery seems to be a non-invasive alternative to the conventional neurosurgery in focal epilepsy.

摘要

两名患有复杂部分性癫痫和颞叶肿瘤的患者计划接受伽玛刀放射外科治疗,术前和术后通过多通道脑磁图(MEG)进行评估。术前发现的癫痫偶极活动中心在局部照射后消失,癫痫发作也随之消失。因此,将立体定向MEG和伽玛刀放射外科相结合似乎是局灶性癫痫传统神经外科手术的一种非侵入性替代方法。

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Physiol Meas. 1993 May;14(2):131-6. doi: 10.1088/0967-3334/14/2/004.
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Applicability of the single equivalent point dipole model to represent a spatially distributed bio-electrical source.
Med Biol Eng Comput. 2001 Sep;39(5):562-70. doi: 10.1007/BF02345147.
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Acta Neurochir (Wien). 1996;138(9):1103-7; discussion 1107-8. doi: 10.1007/BF01412315.