Hoogland H J, Skouby S O
Department of Obstetrics & Gynaecology, University of Limburg, Maastricht, The Netherlands.
Contraception. 1993 Jun;47(6):583-90. doi: 10.1016/0010-7824(93)90025-3.
The trend towards changing the composition of the contraceptive pill in order to decrease side effects might lead to increased ovarian activity. This may decrease reliability. Therefore, a non-invasive method for monitoring the suppressive effect of the pill on ovarian function is warranted. The aim of the present study was to investigate whether or not diagnostic ultrasound might be the method of choice for studying residual ovarian activity during pill use. In 89 women on a low-dose oral contraceptive (30 mcg ethinyl-estradiol (EE)/75 mcg gestodene), the first two months of pill-intake were monitored extensively with diagnostic ultrasound. The study revealed that only one ultrasound investigation was needed during the first week of pill intake to discover all relevant cases of residual ovarian activity. Follow-up investigations are needed to quantify this activity more specifically.
为减少副作用而改变避孕药成分的趋势可能会导致卵巢活性增加。这可能会降低可靠性。因此，需要一种非侵入性方法来监测避孕药对卵巢功能的抑制作用。本研究的目的是调查诊断性超声是否可能是研究服用避孕药期间残余卵巢活性的首选方法。在89名服用低剂量口服避孕药（30微克炔雌醇（EE）/75微克孕二烯酮）的女性中，通过诊断性超声对服药的前两个月进行了广泛监测。研究表明，在服药的第一周只需进行一次超声检查就能发现所有残余卵巢活性的相关病例。需要进行后续调查以更具体地量化这种活性。
