Yao Z H
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1993 Jan;15(1):55-7.
Umbilical metastasis from gynecologic malignancies is very rare. We report fifteen patients with primary gynecologic malignant tumors associated with umbilical metastases treated in this hospital from 1958-1991. 1, including 10 epithelial ovarian cancer. 1 malignant teratoma of the ovary, 2 endometrial carcinoma and 2 squamous cell carcinoma of the cervix. Apart from one patient initially diagnosed as stage 1 endometrial carcinoma, all patients had advanced tumors. Six patients had umbilical lesion present at the time of initial diagnosis of the primary tumor. The main clinical finding is an umbilical nodule or an ulcerated nodule in a diameter less than 2 cm. Usually the prognosis was poor. The average survival from initial diagnosis of umbilical metastasis to death was 14 months in 12 patients. There were 4 cases with longer survival, including one patient with endometrial carcinoma who survived 40 months, and 3 patients with ovarian carcinoma who survived 54, 52, 31 months, respectively. Two cases are surviving with tumor. It indicates that aggressive therapy may prolong survival time, especially in patients with ovarian cancers.
妇科恶性肿瘤的脐部转移非常罕见。我们报告了1958年至1991年在本院接受治疗的15例原发性妇科恶性肿瘤合并脐部转移的患者。其中包括10例上皮性卵巢癌、1例卵巢恶性畸胎瘤、2例子宫内膜癌和2例宫颈鳞状细胞癌。除1例最初诊断为Ⅰ期子宫内膜癌的患者外，所有患者均为晚期肿瘤。6例患者在原发性肿瘤初次诊断时就存在脐部病变。主要临床发现是直径小于2厘米的脐部结节或溃疡结节。通常预后较差。12例患者从脐部转移初次诊断到死亡的平均生存期为14个月。有4例生存期较长，包括1例子宫内膜癌患者存活40个月，3例卵巢癌患者分别存活54、52、31个月。2例患者带瘤生存。这表明积极的治疗可能会延长生存时间，尤其是卵巢癌患者。 1（原文此处数字1指代不明，按原文照译）
