Behtash Nadereh, Mehrdad Nili, Shamshirsaz Amir, Hashemi Razieh, Amouzegar Hashemi Farnaz
Vali-E-Asr Hospital, Tehran, Iran.
Arch Gynecol Obstet. 2008 Nov;278(5):489-91. doi: 10.1007/s00404-008-0617-4. Epub 2008 Apr 1.
Objective cutaneous metastasis from carcinoma of the uterine cervix is an uncommon occurrence. The outcome of patients with skin metastasis is usually poor as they are often associated with locoregional recurrence. This metastasis impairs the quality of life and shortens survival. Consequently, physicians should be aware of the possible existence of skin metastasis in cervical cancer. Clinical suspicion should lead to a careful additional evaluation whenever a cutaneous nodule presents in the course of the disease.
We report a rare case of metastasis from squamous cell carcinoma of cervix to the umbilicus. The patient was diagnosed with stage IIB FIGO. Four months after chemoradiation patient presented with a nodule in the umbilical region. Biopsy performed and metastatic squamous cell carcinoma was diagnosed. Patient underwent salvage therapy with paclitaxel and carboplatin.
To the best of our knowledge, this is a rare reported occurrence of umbilical metastasis in cervical cancer without prior laparotomy or laparoscopy. This metastatic lesion has a grave prognosis and the mean survival is about 3 months like our case.
子宫颈癌的客观皮肤转移并不常见。皮肤转移患者的预后通常较差,因为它们常与局部区域复发相关。这种转移会损害生活质量并缩短生存期。因此,医生应意识到宫颈癌可能存在皮肤转移。在疾病过程中出现皮肤结节时,临床怀疑应促使进行仔细的进一步评估。
我们报告一例罕见的宫颈鳞状细胞癌转移至脐部的病例。该患者被诊断为国际妇产科联盟(FIGO)IIB期。放化疗四个月后,患者脐部出现一个结节。进行活检后诊断为转移性鳞状细胞癌。患者接受了紫杉醇和卡铂的挽救治疗。
据我们所知,这是一例罕见的宫颈癌脐部转移病例,之前未进行过剖腹手术或腹腔镜检查。这种转移性病变预后严重,与我们的病例一样,平均生存期约为3个月。