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[固定应激及适应原性生物活性物质影响下不同年龄大鼠的内分泌系统状态]

[State of the endocrine system in rats of various ages under immobilization stress and influence of adaptogenic biomos].

作者信息

Alesina M Iu, Sukachova O O, Zilberman S Ts, Konovalenko O O, Nesterenko G O, Beskrovnyĭ O M

出版信息

Fiziol Zh (1978). 1993 Jan-Feb;39(1):78-83.

PMID:8335128
Abstract

The effect of administration, of BIOMOS-VJ on the concentration of thyroxine, triiodothyronine, corticosterone, insulin and glucose in the blood serum of the normal state and under conditions of immobilization stress of young and aged Wistar's rats has been studied. The experiments have shown that the administration of preparation prevents the appearance of disturbances in endocrine system of the organism typical of stress such as a decrease in concentration of thyroid hormones and insulin and also a considerable increase in corticosterone and glucose concentration in the blood serum. On the basis of the results indicating the influence of BIOMOS-VJ on the endocrine system of young and aged Wistar's rats it is assumed that this preparation has gero-protected properties.

摘要

研究了BIOMOS-VJ对正常状态以及处于固定应激条件下的幼年和老年Wistar大鼠血清中甲状腺素、三碘甲状腺原氨酸、皮质酮、胰岛素和葡萄糖浓度的影响。实验表明,给予该制剂可防止机体出现典型的应激性内分泌系统紊乱,如甲状腺激素和胰岛素浓度降低,以及血清中皮质酮和葡萄糖浓度显著升高。基于表明BIOMOS-VJ对幼年和老年Wistar大鼠内分泌系统有影响的结果,推测该制剂具有老年保护特性。

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