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[重症肌无力合并哮喘的特殊治疗]

[Unusual treatment for myasthenia gravis associated with asthma].

作者信息

Weiner P, Ganem R, Weiner M

机构信息

Dept. of Medicine A, Hillel Yaffe Medical Center, Hadera.

出版信息

Harefuah. 1993 Apr 15;124(8):474-7, 527.

PMID:8335271
Abstract

Abnormal antibody production is now recognized as the basis of many diseases, among them myasthenia gravis (MG) and a variant of bronchial asthma. It is not unusual to find 2 or even more of these diseases in the same patient. A patient in whom both MG and bronchial asthma were diagnosed is presented. In both diseases the respiratory muscles are mechanically disadvantaged, which may result in severe dyspnea. In our case, despite specific treatment for both diseases severe attacks of dyspnea still occurred. Specific inspiratory muscle training was followed by significant clinical improvement. There was indirect evidence that respiratory muscles can be trained in patients with MG. Thus, patients with MG with respiratory muscle involvement may benefit from respiratory muscle training.

摘要

异常抗体产生现已被确认为许多疾病的基础,其中包括重症肌无力(MG)和支气管哮喘的一种变体。在同一患者中发现两种甚至更多种这些疾病并不罕见。本文介绍了一位同时被诊断患有MG和支气管哮喘的患者。在这两种疾病中,呼吸肌在机械方面都处于劣势,这可能导致严重的呼吸困难。在我们的病例中,尽管对两种疾病都进行了特异性治疗,但仍发生了严重的呼吸困难发作。进行特异性吸气肌训练后,临床症状有了显著改善。有间接证据表明,MG患者的呼吸肌可以得到训练。因此,呼吸肌受累的MG患者可能会从呼吸肌训练中获益。

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1
[Unusual treatment for myasthenia gravis associated with asthma].[重症肌无力合并哮喘的特殊治疗]
Harefuah. 1993 Apr 15;124(8):474-7, 527.
2
[Bronchial asthma complicated by myasthenia gravis].支气管哮喘合并重症肌无力
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Maximal voluntary ventilation in myasthenia gravis.重症肌无力患者的最大自主通气量
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Respiratory muscle training in patients with moderate to severe myasthenia gravis.中重度重症肌无力患者的呼吸肌训练
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MRI and clinical studies of facial and bulbar muscle involvement in MuSK antibody-associated myasthenia gravis.MuSK抗体相关重症肌无力面部及延髓肌受累的MRI与临床研究
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Phrenic and intercostal repetitive nerve stimulation: a useful electroneurophysiological method to detect the respiratory status of myasthenia gravis patients.膈神经和肋间神经重复神经刺激:一种检测重症肌无力患者呼吸状态的有用的神经电生理方法。
Electromyogr Clin Neurophysiol. 2003 Jan-Feb;43(1):9-16.
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Asthma as a cause of persistent dyspnea in treated myasthenia gravis patients.哮喘是治疗后的重症肌无力患者持续呼吸困难的原因。
Eur Neurol. 2012;68(5):300-3. doi: 10.1159/000341834. Epub 2012 Oct 9.
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[Effect of specific inspiratory muscle training on dyspnea and exercise tolerance in congestive heart failure].[特定吸气肌训练对充血性心力衰竭患者呼吸困难及运动耐力的影响]
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