Grant A, von Schoenberg M, Grant H R, Miller R F
Department of Medicine, Ferens Institute University College and Middlesex School of Medicine, Middlesex Hospital, London.
Genitourin Med. 1993 Jun;69(3):208-12. doi: 10.1136/sti.69.3.208.
To investigate the prevalence of radiologically-diagnosed paranasal sinus disease in HIV-1 seropositive patients.
476 patients admitted to a dedicated inpatient unit for HIV and AIDS at the Middlesex Hospital, London, between September 1988 and February 1992.
Retrospective review of patients' case notes and radiological records.
30 patients (6.3%) had radiological evidence of paranasal sinus disease. At the time of admission, sinusitis was in the differential diagnosis in only 12 of the 30 patients; 13 patients were initially diagnosed as having meningitis. Pseudomonas aeruginosa was the causative organism in four patients, all of whom had advanced HIV disease. All four responded to appropriate antibiotics but had early relapse of infection.
Sinusitis is an important and under-recognised cause of morbidity in patients with HIV disease.
调查经放射学诊断的HIV-1血清阳性患者鼻旁窦疾病的患病率。
1988年9月至1992年2月期间，伦敦米德尔塞克斯医院专门收治HIV和艾滋病患者的住院部的476名患者。
对患者病历和放射学记录进行回顾性审查。
30名患者（6.3%）有鼻旁窦疾病的放射学证据。入院时，30名患者中只有12名的鉴别诊断中有鼻窦炎；13名患者最初被诊断为患有脑膜炎。铜绿假单胞菌是4名患者的致病微生物，所有这些患者都患有晚期HIV疾病。所有4名患者对适当的抗生素有反应，但感染早期复发。
鼻窦炎是HIV疾病患者发病的一个重要但未得到充分认识的原因。
