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鼻窦炎的识别与管理。

Recognition and management of sinusitis.

作者信息

Evans K L

机构信息

Department of Otolaryngology, Gloucester Royal Hospital, England.

出版信息

Drugs. 1998 Jul;56(1):59-71. doi: 10.2165/00003495-199856010-00006.

Abstract

Acute sinusitis frequently follows upper respiratory tract infections. Patients complain of headache, facial pain, fever and purulent rhinorrhoea. Diagnosis is based upon the symptoms, and treatment comprises symptomatic relief with analgesics, topical or systemic decongestants and steam inhalation. If indicated, antibiotics should be given for an adequate period of time. Patients with chronic sinusitis complain of a combination of nasal obstruction, rhinorrhoea and postnasal drip associated with intermittent facial pain, with symptoms persisting for 3 months or more. Predisposition to the condition may be caused by rhinitis (allergic or nonallergic) and anatomical variants. Failure of mucociliary transport and sinus ostial obstruction leads to mucosal oedema, mucous hypersecretion and chronic infection. Current treatment aims are to control rhinitis and improve ventilation and function of the sinuses. Rhinitis may be controlled with the long term use of topical corticosteroids, mast cell stabilisers or antihistamines, either alone or in combination. Secretions may be cleared with steam inhalation and/or saline nasal douching. Failure to control chronic sinusitis with medical treatment may indicate surgery. The aim of surgery is to improve ventilation and facilitate drainage of the sinuses, allowing the restoration of normal function. Removal of nasal polyps, reduction of inferior turbinates or septal straightening may be all that is required. Some patients will need endoscopic ethmoidectomy and middle meatal antrostomy. Improved ventilation in the ethmoid infundibulum may help to resolve disease in maxillary and frontal sinuses. Medical treatment of underlying rhinitis will need to be continued postoperatively, often in the long term, while special consideration needs to be paid to sinusitis in children, in relation to dental disease and in the immunosuppressed. Complications of acute and chronic sinusitis include intraorbital and intracranial sepsis. These potentially lethal complications need urgent evaluation with high resolution computerised tomography (CT) scanning, intravenous administration of broad spectrum antibiotics (including anaerobic and microaerophilic cover) and urgent surgical drainage as appropriate.

摘要

急性鼻窦炎常继发于上呼吸道感染。患者会出现头痛、面部疼痛、发热及脓性鼻漏。诊断基于症状,治疗包括使用镇痛药、局部或全身减充血剂以及蒸汽吸入进行症状缓解。如有指征,应给予足够疗程的抗生素。慢性鼻窦炎患者会出现鼻塞、鼻漏和鼻后滴漏,并伴有间歇性面部疼痛,症状持续3个月或更长时间。该病的易患因素可能由鼻炎(过敏性或非过敏性)和解剖变异引起。黏液纤毛运输功能障碍和鼻窦开口阻塞会导致黏膜水肿、黏液分泌过多及慢性感染。目前的治疗目标是控制鼻炎并改善鼻窦的通气和功能。鼻炎可通过长期单独或联合使用局部糖皮质激素、肥大细胞稳定剂或抗组胺药来控制。分泌物可通过蒸汽吸入和/或盐水鼻腔冲洗清除。药物治疗无法控制慢性鼻窦炎时可能需要手术。手术目的是改善通气并促进鼻窦引流,使功能恢复正常。可能只需切除鼻息肉、缩小下鼻甲或矫正鼻中隔。部分患者需要行内镜筛窦切除术和中鼻道上颌窦造口术。改善筛漏斗的通气可能有助于解决上颌窦和额窦的疾病。术后通常需要长期继续治疗潜在的鼻炎,同时对于儿童鼻窦炎、与牙科疾病相关的鼻窦炎以及免疫抑制患者的鼻窦炎需要特别考虑。急慢性鼻窦炎的并发症包括眶内和颅内感染。这些潜在致命并发症需要通过高分辨率计算机断层扫描(CT)进行紧急评估,静脉给予广谱抗生素(包括抗厌氧菌和微需氧菌药物),并在适当时进行紧急手术引流。

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