Kamradt T
Tufts University School of Medicine, New England Medical Center, Division of Rheumatology/Immunology, Boston, MA 02111.
J Rheumatol. 1993 May;20(5):904-6.
T lymphocytes from patients with lepromatous leprosy are anergic to M. leprae antigens. The mechanisms which induce and maintain this antigen specific T cell unresponsiveness in lepromatous leprosy have been the subject of intensive research. Recent insights from work on T cell recognition of antigen, cytokines, and T cell subsets have considerably enhanced the understanding of the immunopathology of lepromatous leprosy.
瘤型麻风患者的T淋巴细胞对麻风杆菌抗原无反应。在瘤型麻风中，诱导并维持这种抗原特异性T细胞无反应性的机制一直是深入研究的课题。近期关于T细胞对抗原的识别、细胞因子及T细胞亚群的研究成果，极大地增进了对瘤型麻风免疫病理学的理解。
