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先天性梅毒:当媒介无法传递信息时。

Congenital syphilis: when the medium fails to transmit the message.

作者信息

Gurry D L, Porter P A, Evans D T

机构信息

Princess Margaret Hospital for Children, Subiaco, WA.

出版信息

Med J Aust. 1993 Jul 19;159(2):121-4.

PMID:8336586
Abstract

OBJECTIVE

To report two cases of congenital syphilis, a disease which should have been prevented.

CLINICAL FEATURES

Two infants, both from the country, presented to Princess Margaret Hospital for Children. Case 1, a boy of five months, had unexplained fractures of radius and clavicle, suggesting non-accidental injury, a belief which lasted until skeletal survey showed widespread bone disease. Exact diagnosis became clear after serological studies. Case 2, an Aboriginal baby of six weeks, came with more classic symptoms and signs--rhinorrhea, rash with desquamation, irritability, anaemia, and lack of movement in an upper limb; the serological diagnosis already made.

INTERVENTION AND OUTCOME

Both infants (and their mothers) were treated with appropriate antibiotics and the symptoms resolved.

CONCLUSIONS

The first case was a challenge to the system for handling suspected child abuse; the second will be a challenge to the follow-up system in a remote area of Western Australia. The delay in diagnosis occurred because the results of the serological tests for syphilis were not appreciated and acted upon. The reports have become complex, consisting of acronyms and numbers which do not convey meaning to clinicians who receive them. Each report should translate the terms and endeavour to interpret the results, to aid prevention of congenital syphilis in the antenatal period or to give early diagnosis and accurate, efficient treatment of the affected infant.

摘要

目的

报告两例先天性梅毒病例,这是一种本应可预防的疾病。

临床特征

两名婴儿均来自农村地区,前往玛格丽特公主儿童医院就诊。病例1是一名五个月大的男婴,桡骨和锁骨出现不明原因骨折,疑似受到非意外伤害,这种看法一直持续到骨骼检查显示存在广泛的骨病。血清学研究后明确了确切诊断。病例2是一名六周大的原住民婴儿,出现了更典型的症状和体征——流涕、伴有脱屑的皮疹、易激惹、贫血以及上肢活动受限;血清学诊断已明确。

干预与结果

两名婴儿(及其母亲)均接受了适当的抗生素治疗,症状得以缓解。

结论

首例病例对处理疑似虐待儿童的系统构成了挑战;第二例病例对西澳大利亚偏远地区的随访系统构成了挑战。诊断延迟是因为梅毒血清学检测结果未得到重视和及时处理。报告变得复杂,包含首字母缩略词和数字,对于接收报告的临床医生而言并无意义。每份报告都应翻译这些术语并努力解读结果,以协助在产前预防先天性梅毒,或对受影响的婴儿进行早期诊断及准确、有效的治疗。

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