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女性会因胎儿畸形而终止妊娠后感到悲伤吗?一项对照研究。

Do women grieve after terminating pregnancies because of fetal anomalies? A controlled investigation.

作者信息

Zeanah C H, Dailey J V, Rosenblatt M J, Saller D N

机构信息

Department of Psychiatry, Women & Infants Hospital, Providence, Rhode Island.

出版信息

Obstet Gynecol. 1993 Aug;82(2):270-5.

PMID:8336876
Abstract

OBJECTIVE

To test the hypothesis that grief responses do not differ between women who terminate their pregnancies for fetal anomalies and women who experience spontaneous perinatal losses.

METHODS

A case-control study was conducted. Twenty-three women who underwent terminations through the genetics service of a tertiary referral obstetric hospital from January 1991 to April 1992 were assessed psychiatrically 2 months after the termination. The grief responses of these women on the Perinatal Grief Scale and the Beck Depression Inventory were compared to a demographically similar group of women assessed 2 months after they experienced spontaneous perinatal loss. Differences between the groups were assessed through one-way analysis of covariance.

RESULTS

After matching women in the two groups, it became clear that women who terminated for fetal anomalies were significantly older than women in the comparison group, and age was inversely correlated with intensity of grief. Therefore, age was covaried in comparing the grief responses of women in the two groups. Neither statistically significant nor clinically meaningful differences were found in symptomatology between the groups. By the time of assessment, four of 23 women (17%) who terminated their pregnancies were diagnosed with a major depression, and five of 23 (22%) had sought psychiatric treatment.

CONCLUSIONS

Women who terminate pregnancies for fetal anomalies experience grief as intense as those who experience spontaneous perinatal loss, and they may require similar clinical management. Diagnosis of a fetal anomaly and subsequent termination may be associated with psychological morbidity.

摘要

目的

检验以下假设,即因胎儿异常而终止妊娠的女性与经历围产期自然流产的女性在悲伤反应上没有差异。

方法

进行了一项病例对照研究。1991年1月至1992年4月期间,通过一家三级转诊产科医院的遗传学服务进行终止妊娠的23名女性在终止妊娠2个月后接受了精神科评估。将这些女性在围产期悲伤量表和贝克抑郁量表上的悲伤反应与一组在经历围产期自然流产2个月后接受评估的、人口统计学特征相似的女性进行比较。通过单因素协方差分析评估两组之间的差异。

结果

在对两组女性进行匹配后,很明显因胎儿异常而终止妊娠的女性比对照组女性年龄显著更大,且年龄与悲伤强度呈负相关。因此,在比较两组女性的悲伤反应时对年龄进行了协变量调整。两组在症状学方面既未发现统计学上的显著差异,也未发现具有临床意义的差异。到评估时,23名终止妊娠的女性中有4名(17%)被诊断为重度抑郁症,23名中有5名(22%)寻求过精神科治疗。

结论

因胎儿异常而终止妊娠的女性所经历的悲伤与经历围产期自然流产的女性一样强烈,她们可能需要类似的临床管理。胎儿异常的诊断及随后的终止妊娠可能与心理疾病有关。

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