Tsuji M
Department of Radiology, Tokai University, School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1993 Jun 25;53(6):667-78.
Atrial septal defect (ASD) is one of the most common congenital cardiac anomalies encountered in adulthood. The evaluation of the pulmonary hypertension in ASD is clinically important for operative indication and prognosis. The pulmonary vasculature in chest radiographs in patients with ASD is characterized as dilatation of the central pulmonary arteries and increase of the peripheral pulmonary vessels in patients without pulmonary arterial hypertension (PH) and constriction of the peripheral pulmonary arteries in those with pulmonary hypertension. While the dilatation of the main pulmonary artery occurs in the patients both with and without pulmonary hypertension, its precise radiographic evaluation with regard to the morphological and hemodynamic change of the right ventricle and pulmonary arteries has not been reported. This study was to determine if the contour of the main pulmonary artery segment of the cardiac silhouette in the conventional frontal chest radiograph could be used 1) as indicators of PH or raised right ventricular pressure and 2) as a reliable base for evaluation of the size of the right ventricule (RV) in ASD. The intersection of the line (line A) drawn tangentially to the lateral lower margin of the main pulmonary artery segment to the horizontal line at the left hemidiaphragm is closely related to the apex of RV as measured by right ventricular angiography in supine position. The ratios of the distance of the intersection from the midline of the frontal chest radiograph to the internal diameter of the left hemithorax in normal subjects were 0.50 +/- 0.08 (mean +/- standard deviation) for male and 0.54 +/- 0.09 for female. The ratio increased with increasing left-to-right shunt [0.59(Qp/QS < 2), and 0.71 (Qp/QS > 2)] and shows a tendency of decrease with raised right ventricular systolic pressure (0.52-0.64 in normal subjects and patients with mild raised right ventricular systolic pressure and 0.43 in patients with severe raised right ventricular systolic pressure). The measurement of the angle of the line A from the vertical line tends to show increasing decrease with raised pulmonary arterial and right ventricular systolic pressure (20.1 degrees +/- 4.9 in mild PH and 10.3 degrees +/- 4.1 in moderate to severe PH). The decrease of the angle of the line A to the vertical line was well correlated with conventional radiographic criteria of the right and left central pulmonary arteries of PH.(ABSTRACT TRUNCATED AT 400 WORDS)
房间隔缺损(ASD)是成人中最常见的先天性心脏畸形之一。评估ASD患者的肺动脉高压对于手术指征和预后具有重要的临床意义。ASD患者胸部X线片上的肺血管系统特征为:无肺动脉高压(PH)的患者表现为中央肺动脉扩张和外周肺血管增多,而有肺动脉高压的患者则表现为外周肺动脉狭窄。虽然无论有无肺动脉高压,患者的主肺动脉都会发生扩张,但关于其右心室和肺动脉形态及血流动力学变化的精确影像学评估尚未见报道。本研究旨在确定传统胸部正位X线片中心脏轮廓的主肺动脉段轮廓是否可用于:1)作为PH或右心室压力升高的指标;2)作为评估ASD患者右心室(RV)大小的可靠依据。与主肺动脉段外侧下缘相切并与左半膈肌处水平线相交的直线(直线A)的交点,与仰卧位右心室造影测量的RV心尖密切相关。正常男性受试者中,该交点到胸部正位X线片中线的距离与左半胸廓内径的比值为0.50±0.08(均值±标准差),女性为0.54±0.09。该比值随左向右分流增加而升高[0.59(Qp/QS<2),0.71(Qp/QS>2)],并随右心室收缩压升高呈下降趋势(正常受试者和轻度右心室收缩压升高患者为0.52 - 0.64,重度右心室收缩压升高患者为0.43)。直线A与垂直线夹角的测量结果显示,随着肺动脉和右心室收缩压升高,夹角逐渐减小(轻度PH为20.1°±4.9°,中度至重度PH为10.3°±4.1°)。直线A与垂直线夹角的减小与PH时左右中央肺动脉的传统影像学标准密切相关。(摘要截选至400字)