Suárez Tembra M, Yuste Ara J R, Lucas Ros I
Departamento de Medicina Interna, Facultad de Medicina, Universidad de Navarra, Pamplona.
Rev Clin Esp. 1993 Jun;193(1):28-30.
Obliterant Bronchiolitis is an anatomo-clinical entity known years ago. It is recognized as a evolutive form of different processes, including Extrinsic Allergic Alveolitis, Pneumonitis due to gas inhalation, viral processes and Rheumatoid Lung. It has been recently identified as a disease with specific characteristics in the context of interstitial idiopathic pneumonia with bronchiolar involvement and a distinctive anatomo-pathological character. From the clinical and radiological point of view it requires a broad differential diagnosis, which is confirmed definitively in the anatomopathological exam obtained through minithoracotomy. Therapeutic response to corticosteroids is good even thought it shows a trend to relapse when they are decreased or stopped. We discuss the cases of three patients who were studied recently, showing their clinical, radiological and anatomopathological features together with the therapeutic response, which is positive, in different periods of the evolution course.
闭塞性细支气管炎是一种多年前就已为人所知的解剖学 - 临床实体。它被认为是不同病程的一种演变形式,包括外源性过敏性肺泡炎、气体吸入性肺炎、病毒感染病程以及类风湿性肺病。最近,它在伴有细支气管受累的特发性间质性肺炎背景下被确定为一种具有特定特征且有独特解剖病理学特征的疾病。从临床和放射学角度来看,它需要进行广泛的鉴别诊断,而通过小开胸手术获得的解剖病理学检查才能最终确诊。对皮质类固醇的治疗反应良好,尽管在减量或停药时显示出复发趋势。我们讨论了最近研究的三名患者的病例,展示了他们在病程不同阶段的临床、放射学和解剖病理学特征以及积极的治疗反应。