Galvao L M, Nunes R M, Cançado J R, Brener Z, Krettli A U
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):220-3. doi: 10.1016/0035-9203(93)90501-g.
A complement-mediated lysis test (CoML) using living trypomastigotes was compared with conventional serological methods and with haemoculture. Over a 10 years follow-up period evidence was obtained which supported the view that chagasic patients, treated with nitroheterocyclic drugs, in whom CoML had reverted to negative, might be considered cured despite conventional serology remaining positive.
使用活的锥鞭毛体进行的补体介导溶血试验(CoML)与传统血清学方法及血培养进行了比较。在长达10年的随访期内,获得的证据支持以下观点:尽管传统血清学检查仍为阳性,但接受硝基杂环药物治疗且CoML转为阴性的恰加斯病患者可被视为已治愈。