Sinha A A, Erickson A W, Seal U S
J Reprod Fertil. 1977 Jan;49(1):51-4. doi: 10.1530/jrf.0.0490051.
Ultrastructural study of the Leydig cells of nonbreeding crabeater, leopard and Ross seals showed that three types of cells could be distinguished. Type I cells possessed the cytological features typical of steroid-secreting cells. Type II cells exhibited various features of degeneration, e.g. accumulation of large amounts of lipofuscin granules (residual bodies), lipid droplets, secondary lysosomes, rectangular crystalloids, and previously undescribed 'peculiar bodies'. These cellular inclusions and debris were released into the interstitium to be phagocytosed by macrophages and/or resorbed by the lymphatics. Type III Leydig cells contained large amounts of lipid droplets, sparse cytoplasmic organelles and essentially became lipid storage cells.
对非繁殖期食蟹海豹、豹海豹和罗斯海豹的睾丸间质细胞进行超微结构研究发现，可区分出三种类型的细胞。I型细胞具有类固醇分泌细胞的典型细胞学特征。II型细胞呈现出各种退化特征，例如大量脂褐素颗粒（残余小体）、脂滴、次级溶酶体、矩形晶体以及此前未描述的“特殊小体”的积累。这些细胞内含物和碎片被释放到间质中，被巨噬细胞吞噬和/或被淋巴管吸收。III型睾丸间质细胞含有大量脂滴，细胞质细胞器稀少，基本上变成了脂质储存细胞。
