Geller A J, Kolts B E, Achem S R, Wears R
Department of Medicine, University of Florida Health Science Center, Jacksonville.
Am J Gastroenterol. 1993 Aug;88(8):1184-7.
Colon polyps are commonly detected in the workup of fecal occult blood (FOB). It is, however, unclear whether colon polyps can adequately explain FOB. Our aim was to determine the frequency of upper gastrointestinal (UGI) pathology in patients with and without UGI symptoms and with and without risk factors for UGI pathology (such as smoking, drinking alcohol, taking nonsteroidal anti-inflammatory medications, or the presence of associated chronic diseases) who have colon polyps and FOB. Among our 67 study patients with colon polyps and FOB, 79% had associated UGI lesions. Presence or absence of UGI symptoms, risk factors associated with UGI lesions, and polyp characteristics such as size, location, number, and histology, did not appreciably affect this high frequency. Ulcers were the most common lesions in both symptomatic and asymptomatic patients. We conclude that patients with colon polyps found in the evaluation of FOB are likely to have concomitant UGI pathology, and UGI workup should be considered in both symptomatic and asymptomatic patients.
结肠息肉通常在粪便潜血（FOB）检查中被发现。然而，目前尚不清楚结肠息肉是否能充分解释粪便潜血阳性。我们的目的是确定在有或无上消化道（UGI）症状以及有或无上消化道病变风险因素（如吸烟、饮酒、服用非甾体类抗炎药或存在相关慢性病）的结肠息肉和粪便潜血阳性患者中，上消化道病变的发生率。在我们67例患有结肠息肉和粪便潜血阳性的研究患者中，79%伴有上消化道病变。上消化道症状的有无、与上消化道病变相关的风险因素以及息肉的特征（如大小、位置、数量和组织学类型），并未明显影响这一高发生率。溃疡是有症状和无症状患者中最常见的病变。我们得出结论，在粪便潜血检查评估中发现结肠息肉的患者很可能同时存在上消化道病变，有症状和无症状患者均应考虑进行上消化道检查。
