Fringes B, Gorgas K
Department of Human Genetics, Yale University, Medical School, New Haven, CT 06510.
Ann Anat. 1993 Jun;175(3):231-5. doi: 10.1016/s0940-9602(11)80007-5.
The occurrence, localization and organization of crystalloid smooth endoplasmic reticulum (SER) membrane aggregates in the male quail uropygial gland was investigated by electron microscopy. The lattice-like structures exhibiting a hexagonal honeycomb pattern are regularly found in the perinuclear region of the fully developed intermediate cell (type II) which is most effective in lipid biosynthesis and constitutes the middle layers of the stratified glandular epithelium undergoing sebaceous transformation. The crystalloids frequently exhibit a rectangular shape and tend to cluster, the latter exceeding 5 microns in length. They are composed of sets of highly ordered and densely packed tubular SER profiles. Diaminobenzidine (DAB) stained peroxisomes exhibit a close spatial relationship to the borders of crystalloids, but the organelles do not participate in the formation of these grid-like structures. The functional significance of the conformational change of the SER organization is not known. Local accumulation of specific lipogenic enzymes within this functional SER domain is discussed.
通过电子显微镜研究了雄性鹌鹑尾脂腺中晶体样滑面内质网（SER）膜聚集体的发生、定位和组织情况。在完全发育的中间细胞（II型）的核周区域经常发现呈现六边形蜂窝状图案的晶格状结构，这种细胞在脂质生物合成中最为有效，构成了经历皮脂腺转化的复层腺上皮的中间层。这些晶体经常呈现矩形形状并倾向于聚集，后者长度超过5微米。它们由高度有序且紧密排列的管状SER轮廓组成。二氨基联苯胺（DAB）染色的过氧化物酶体与晶体边界呈现紧密的空间关系，但这些细胞器不参与这些网格状结构的形成。SER组织构象变化的功能意义尚不清楚。讨论了特定脂肪生成酶在这个功能性SER区域内的局部积累情况。
