Chen F, Sheridan B, Nankervis J
Noel Newton Department of Head and Neck Surgery, St Vincent's Hospital, Sydney, New South Wales, Australia.
Aust N Z J Surg. 1993 Aug;63(8):614-6. doi: 10.1111/j.1445-2197.1993.tb00468.x.
Carcinoma of the thyroglossal tract is a rare entity. Three patients with thyroglossal cyst carcinomas are presented and the features of the disease, as reported in the literature, are discussed. Epidemiologically, females are more often affected than males and the average age of the patients described lies in the fourth decade. The aetiology is obscure, although previous irradiation is a possible risk factor. Carcinoma of the thyroglossal tract should also be suspected in patients with irregular masses. Pre-operative evaluation may include a thyroid scan and fine needle aspiration cytological examination of the cyst fluid. These tests, if positive, may alter the basic approach of the Sistrunk procedure to encompass thyroidectomy or wider margins. Neck dissection is preferred for cervical nodal disease. Adjuvant radiotherapy or radio-iodine is added if indicated by the histology, and the patient receives suppressive thyroxine therapy thereafter.
甲状舌管癌是一种罕见的疾病。本文介绍了3例甲状舌管囊肿癌患者，并讨论了文献中报道的该疾病的特征。从流行病学角度来看，女性比男性更易患病，所描述患者的平均年龄在40岁左右。病因尚不明确，尽管既往接受过放疗可能是一个危险因素。对于有不规则肿块的患者，也应怀疑甲状舌管癌。术前评估可能包括甲状腺扫描和对囊液进行细针穿刺细胞学检查。这些检查若呈阳性，可能会改变Sistrunk手术的基本术式，以包括甲状腺切除术或更宽的切缘。对于颈部淋巴结疾病，首选颈部清扫术。如果组织学检查有指征，则加用辅助放疗或放射性碘治疗，此后患者接受甲状腺素抑制治疗。
