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Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?

作者信息

Bertilsson L, Kalow W

出版信息

Clin Pharmacol Ther. 1993 May;53(5):608-10. doi: 10.1038/clpt.1993.77.

DOI:10.1038/clpt.1993.77
PMID:8338569
Abstract
摘要

相似文献

1
Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?为什么地西泮代谢和多态性S-美芬妥因羟化在白种人和韩国人群中相互关联,而在中国人群中却没有这种关联?
Clin Pharmacol Ther. 1993 May;53(5):608-10. doi: 10.1038/clpt.1993.77.
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Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics.韩国人群中S-美芬妥因羟化缺乏症的发生率及地西泮药代动力学的表型间差异。
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CYP2C19 genotype does not represent a genetic predisposition in idiopathic systemic lupus erythematosus.细胞色素P450 2C19基因型并非特发性系统性红斑狼疮的遗传易感性因素。
Ann Rheum Dis. 1999 Mar;58(3):182-5. doi: 10.1136/ard.58.3.182.
3
Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19.
多态性药物氧化的地理/种族差异。细胞色素P450(CYP)2D6和2C19的现有知识状况。
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4
Interphenotype differences in disposition and effect on gastrin levels of omeprazole--suitability of omeprazole as a probe for CYP2C19.奥美拉唑在处置方面的表型差异及其对胃泌素水平的影响——奥美拉唑作为CYP2C19探针的适用性
Br J Clin Pharmacol. 1995 May;39(5):511-8. doi: 10.1111/j.1365-2125.1995.tb04488.x.