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Ultrastructure of spontaneously differentiated human malignant melanocytes cultured from primary tumors.

作者信息

Aubert C, Chirieceanu E, Foa C, Delain E

出版信息

J Natl Cancer Inst. 1977 Jan;58(1):29-35. doi: 10.1093/jnci/58.1.29.

DOI:10.1093/jnci/58.1.29
PMID:833862
Abstract

Ultrastructural study of early subcultures and established lines of human malignant melanocytes derived from primary tumors showed that melanocytes passed through a phase of dedifferentiation during which they took on a fibroblast-like appearance; then they had a phase of spontaneous redifferentiation. The fibroblast-like cells were characterized by the presence of network-like organelles in their cytoplasm, and the melanocytes by melanosomes.

摘要

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