Ultrastructure of spontaneously differentiated human malignant melanocytes cultured from primary tumors.
作者信息
Aubert C, Chirieceanu E, Foa C, Delain E
出版信息
J Natl Cancer Inst. 1977 Jan;58(1):29-35. doi: 10.1093/jnci/58.1.29.
PMID:833862
Abstract
Ultrastructural study of early subcultures and established lines of human malignant melanocytes derived from primary tumors showed that melanocytes passed through a phase of dedifferentiation during which they took on a fibroblast-like appearance; then they had a phase of spontaneous redifferentiation. The fibroblast-like cells were characterized by the presence of network-like organelles in their cytoplasm, and the melanocytes by melanosomes.
摘要
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