Satoh T, Yokozeki H, Katayama I, Nishioka K
Department of Dermatology, School of Medicine, Tokyo Medical and Dental University, Japan.
Br J Dermatol. 1993 Jun;128(6):693-5. doi: 10.1111/j.1365-2133.1993.tb00268.x.
We report a Japanese patient with skin-coloured keratotic papules on the hands and feet, and pronounced hyperkeratosis of the palms and soles. There was no evidence of fragmentation of dermal elastic tissue on histology. Freckle-like pigmentation was also present on the dorsa of the hands and feet, and this appeared to be closely related to the keratotic disorder. The mode of inheritance was autosomal dominant. We consider our case to be a new variant of familial punctate acrokeratoderma, associated with a pigmentary disorder.
我们报告了一名日本患者，其手脚有肤色角化丘疹，手掌和脚底有明显的角化过度。组织学检查未发现真皮弹性组织断裂的证据。手脚背部也有雀斑样色素沉着，这似乎与角化性疾病密切相关。遗传方式为常染色体显性遗传。我们认为我们的病例是家族性点状肢端角化病的一种新变体，与色素沉着障碍有关。
