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骨质疏松症伴神经功能缺损的脊柱骨折

Spine fracture with neurological deficit in osteoporosis.

作者信息

Heggeness M H

机构信息

Department of Orthopaedic Surgery, Baylor College of Medicine, Houston, TX 77030.

出版信息

Osteoporos Int. 1993 Jul;3(4):215-21. doi: 10.1007/BF01623679.

DOI:10.1007/BF01623679
PMID:8338978
Abstract

The literature suggests that spinal fractures acquired after minimal trauma in osteoporotic patients cause neurological problems only extremely rarely. This report describes 9 patients with severe osteoporosis in whom minimal trauma led to a fracture of the thoracic or lumbar spine causing significant neurological deficit. All patients presented originally with isolated back pain after minimal trauma. Initial radiographs documented what appeared to be 'benign' compression fractures with minimal loss of vertebral height. Over the following 1-12 weeks all patients described a gradual onset of severe radicular pain which was subsequently associated with profound lower extremity weakness in 7 cases. Repeat radiographs revealed advanced collapse of the fractured level. CT and MRI images revealed violation of the posterior cortex of the vertebrae with retropulsion of bone into the spinal canal. In 2 cases, two simultaneous fractures of this kind were noted; in both of these cases the fractures occurred at adjacent levels. The upper lumbar spine was most frequently involved. This relatively small series suggests that caution should be used in the assessment of benign-appearing compression fractures in osteoporotic patients. The delayed appearance of neurological signs and symptoms may lead to a late or missed diagnosis. The onset of back pain in an elderly patient quite frequently represents the acquisition of a fracture; subsequent complaints of leg pain or lower extremity dysfunction may indicate progression of such a fracture, with compromise of the neutral elements.

摘要

文献表明,骨质疏松患者在遭受轻微创伤后发生的脊柱骨折极少导致神经问题。本报告描述了9例严重骨质疏松患者,他们在遭受轻微创伤后导致胸腰椎骨折并引起明显的神经功能缺损。所有患者最初均在轻微创伤后出现孤立的背痛。最初的X线片显示为“良性”压缩性骨折,椎体高度仅有轻微丢失。在接下来的1至12周内,所有患者均描述了严重神经根性疼痛的逐渐发作,随后7例患者出现了严重的下肢无力。复查X线片显示骨折节段进一步塌陷。CT和MRI图像显示椎体后皮质破坏,骨块向后突入椎管。2例患者出现了两个同时发生的此类骨折;在这两例中,骨折均发生在相邻节段。上腰椎最常受累。这个相对较小的系列研究提示,在评估骨质疏松患者看似良性的压缩性骨折时应谨慎。神经体征和症状的延迟出现可能导致诊断延迟或漏诊。老年患者背痛的发作常常意味着发生了骨折;随后出现的腿痛或下肢功能障碍的主诉可能表明此类骨折进展,伴有神经结构受损。

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