Klersy C, Marchianò V, Negroni M S, Menicanti L, Chimienti M, Comelli M, De Ambroggi L
Centro Cardiovascolare E Malan, Ospedale Clinicizzato San Donato, Università degli Studi, Milano.
Cardiologia. 1993 Mar;38(3):179-84.
Ventricular late potentials recorded on the body surface in patients with old myocardial infarction (MI) are considered to reflect slow conduction, due to the presence in the infarct border zone of viable myocardium within scarred tissue. To assess the prevalence of late potentials in a population with old MI and no malignant arrhythmias and to verify whether myocardial revascularization may influence the substrate responsible for the occurrence of late potentials, 80 patients with old MI (75 males, 5 females), aged 55 +/- 9 years, undergoing coronary surgery, were studied. A Marquette MAC15 HiRes electrocardiogram recorder was used to identify late potentials before and after surgery. Late potentials were defined following the most accepted criteria reported in the literature. Statistical analysis was performed using logistic regression to determine the association of several clinical, hemodynamic and surgical variables with the presence of late potentials. Late potentials were present in 28 patients (35%) before surgery and disappeared in 11 (39%) after surgery. Inferior MI and female sex were the only independent predictors of the presence of preoperative late potentials. On the other hand, persistence of late potentials after surgery was related to the presence of inferior MI and left ventricle aneurysm. These data suggest that revascularization is capable of abolishing late potentials, probably due to functional recovery of perinecrotic hibernated myocardium. With particular anatomic conditions (inferior MI, aneurysm), this functional recovery seems not to be sufficient for the disappearance of late potentials.
陈旧性心肌梗死(MI)患者体表记录到的心室晚电位被认为反映了缓慢传导,这是由于瘢痕组织内梗死边缘区存在存活心肌。为了评估陈旧性MI且无恶性心律失常人群中心室晚电位的患病率,并验证心肌血运重建是否会影响导致晚电位出现的基质,我们对80例年龄为55±9岁、接受冠状动脉手术的陈旧性MI患者(75例男性,5例女性)进行了研究。使用Marquette MAC15 HiRes心电图记录仪在手术前后识别晚电位。晚电位根据文献中最被认可的标准进行定义。采用逻辑回归进行统计分析,以确定几个临床、血流动力学和手术变量与晚电位存在之间的关联。术前28例患者(35%)存在晚电位,术后11例(39%)消失。下壁心肌梗死和女性是术前晚电位存在的唯一独立预测因素。另一方面,术后晚电位的持续与下壁心肌梗死和左心室室壁瘤的存在有关。这些数据表明,血运重建能够消除晚电位,这可能是由于梗死周围冬眠心肌的功能恢复。在特定的解剖条件下(下壁心肌梗死、室壁瘤),这种功能恢复似乎不足以使晚电位消失。