Lomama E, Helft G, Bernard J M, Chokron S, Tabone X, Nemattalah H, Metzger J P, Vacheron A
Centre médical des Pins, Lamotte-beuvron.
Arch Mal Coeur Vaiss. 1995 Sep;88(9):1267-72.
It has been shown that the presence of ventricular late potentials is a predictive factor of ventricular tachycardia and sudden death after myocardial infarction. The value of thrombolysis in the reduction of the prevalence of ventricular late potentials is now well established. However, the effects of other modes of revascularisation is less well known and more controversial. The authors undertook a retrospective study of 139 consecutive patients undergoing coronary angiography after primary myocardial infarction. The presence of ventricular late potentials fulfilling two of the three usual criteria was sought after a revascularisation procedure. The overall prevalence of ventricular late potentials was 30.9%. This was not affected either by the site of infarction of by the single or multiple character of the coronary artery disease. In addition, the left ventricular ejection fraction was not significantly different in patients with positive ventricular late potentials compared with the others. On the other hand, revascularisation of the culprit lesion responsible for the infarction was strongly correlated with a lower incidence of ventricular late potentials (p < 10 (-5)). In particular, the different incidence of positive late potentials between the dilated (9.3%) and non-dilated group (49.2%) was statistically significant (p < 10 (-6)) without any correlation to the single or multiple character of the coronary disease. The authors discuss the different reports in the literature concerning the effects of angioplasty and coronary bypass surgery on the incidence of ventricular late potentials. Conclusion; the review of the literature shows that thrombolysis significantly reduces the incidence of late potentials after myocardial infarction and the present study suggests that angioplasty and coronary bypass surgery may also be effective.
已表明心室晚电位的存在是心肌梗死后室性心动过速和猝死的预测因素。溶栓在降低心室晚电位患病率方面的价值现已得到充分证实。然而,其他血管重建方式的效果鲜为人知且更具争议性。作者对139例急性心肌梗死后连续接受冠状动脉造影的患者进行了一项回顾性研究。在血管重建术后,寻找符合三项常用标准中两项的心室晚电位。心室晚电位的总体患病率为30.9%。这不受梗死部位或冠状动脉疾病单支或多支病变特征的影响。此外,心室晚电位阳性患者的左心室射血分数与其他患者相比无显著差异。另一方面,梗死相关罪犯病变的血管重建与心室晚电位发生率较低密切相关(p < 10(-5))。特别是,扩张组(9.3%)和未扩张组(49.2%)之间阳性晚电位的不同发生率具有统计学意义(p < 10(-6)),且与冠状动脉疾病的单支或多支病变特征无关。作者讨论了文献中关于血管成形术和冠状动脉搭桥手术对心室晚电位发生率影响的不同报道。结论:文献综述表明溶栓可显著降低心肌梗死后晚电位的发生率,本研究提示血管成形术和冠状动脉搭桥手术也可能有效。