紫菀素A和B，来自紫菀的抗肿瘤环五肽。
Astins A and B, antitumor cyclic pentapeptides from Aster tataricus.
作者信息
Morita H, Nagashima S, Takeya K, Itokawa H
机构信息
Tokyo College of Pharmacy, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1993 May;41(5):992-3. doi: 10.1248/cpb.41.992.
PMID:8339347
Abstract
Two novel antitumor chlorine- and alloThr-containing cyclic pentapeptides, named astins A and B, both of which were isomers and took a cis configuration in one of the amide bonds, were isolated from Aster tataricus together with astin C. Their structures were solved by spectroscopic analysis and chemical degradation.
摘要
从紫菀中分离出两种新型含氯和别苏氨酸的抗肿瘤环五肽，命名为紫菀素A和B，它们均为异构体，且其中一个酰胺键呈顺式构型，同时还分离出了紫菀素C。通过光谱分析和化学降解确定了它们的结构。
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