Rosenberg A, Grätz K W, Sailer H F
Department of Maxillo-Facial Surgery, University of Zurich, Switzerland.
Int J Oral Maxillofac Surg. 1993 Jun;22(3):185-8. doi: 10.1016/s0901-5027(05)80249-8.
A prospective study of 32 patients was performed to analyze black pigmentation in the soft tissue covering titanium miniplates. This soft tissue was compared with the soft tissue covering Champy stainless steel plates. All plates were removed 8 months after application. Macroscopically visible pigmentation was found in 25.6% of the soft tissue covering titanium miniplates and in none of the soft tissue covering Champy stainless steel plates. Microscopically visible pigmentation was found in 71.8% of the soft tissue covering titanium miniplates and in 65.3% of the soft tissue covering Champy stainless steel plates. Energy-dispersive x-ray analysis of the soft tissue covering titanium miniplates revealed only the presence of titanium dioxide. In the soft tissue near Champy stainless steel plates, chromium, nickel, iron, and molybdenum were found. Electron microscopy showed titanium dioxide to be mainly deposited between the collagen fibers, whereas stainless steel particles were mainly found in giant cells.
对32例患者进行了一项前瞻性研究，以分析覆盖钛微型钢板的软组织中的黑色色素沉着情况。将该软组织与覆盖尚皮不锈钢板的软组织进行比较。所有钢板在植入8个月后取出。在覆盖钛微型钢板的软组织中，25.6%出现了肉眼可见的色素沉着，而覆盖尚皮不锈钢板的软组织中均未出现。在覆盖钛微型钢板的软组织中，71.8%出现了显微镜下可见的色素沉着，在覆盖尚皮不锈钢板的软组织中，这一比例为65.3%。对覆盖钛微型钢板的软组织进行能量色散X射线分析，结果仅显示存在二氧化钛。在尚皮不锈钢板附近的软组织中，发现了铬、镍、铁和钼。电子显微镜显示，二氧化钛主要沉积在胶原纤维之间，而不锈钢颗粒主要存在于巨细胞中。
