Gendrel D
Département de pédiatrie, hôpital Saint-Vincent-de-Paul, Paris.
Rev Prat. 1993 Feb 15;43(4):450-2.
Prolonged or recurrent typhoid fever and mainly salmonella septicaemia usually regarded as minor, or even episodes of salmonelluria are not uncommon in patients infested with Schistosoma spp. In such cases the salmonella infection is often apparently resistant to antibiotic therapy. Schistosoma-salmonella interactions have been described with all species of schistosoma, notably S. haematobium, S. mansoni, S. intercalatum and S. japonicum. The adult worms of schistosoma live in the mesenteric venous plexuses and, in some particular sites, salmonellas are electively stuck onto the outer wall of adult schistosomas. As a result of this, salmonella septicaemia is facilitated and sustained by the schistosomal infestation, and several varieties of salmonella may be involved. These salmonella infections cannot be cured without treatment of the associated schistosomiasis.
在感染血吸虫的患者中,长期或反复出现的伤寒热以及主要为沙门菌败血症(通常被视为轻症),甚至沙门菌尿症发作都并不罕见。在这些情况下,沙门菌感染往往明显对抗生素治疗耐药。已描述了血吸虫与沙门菌之间的相互作用,涉及所有血吸虫种类,尤其是埃及血吸虫、曼氏血吸虫、间插血吸虫和日本血吸虫。血吸虫成虫生活在肠系膜静脉丛中,在某些特定部位,沙门菌会选择性地黏附在成虫血吸虫的外壁上。由此,血吸虫感染促进并维持了沙门菌败血症,可能涉及多种沙门菌。若不治疗相关的血吸虫病,这些沙门菌感染就无法治愈。