中风急性期的高血糖并非由应激引起。
Hyperglycemia in the acute phase of stroke is not caused by stress.
作者信息
van Kooten F, Hoogerbrugge N, Naarding P, Koudstaal P J
机构信息
Department of Neurology, University Hospital Rotterdam, Dijkzigt, The Netherlands.
出版信息
Stroke. 1993 Aug;24(8):1129-32. doi: 10.1161/01.str.24.8.1129.
BACKGROUND AND PURPOSE
Hyperglycemia in the acute phase of stroke is associated with poor outcome. Whether hyperglycemia in nondiabetic stroke patients is caused by stress is controversial.
METHODS
We studied glucose levels and glycosylated hemoglobin in 91 consecutive patients with acute stroke admitted within 24 hours after onset of symptoms. In 27 unselected patients we also measured catecholamines on days 1 and 3 after onset.
RESULTS
Hyperglycemia was found in 39 (43%) of the patients, 55% of whom either had diabetes mellitus or latent diabetes; the others had idiopathic hyperglycemia. Norepinephrine levels were associated with the severity of the stroke (P = .005) and with hypertension (P = .03) but not with glucose levels, irrespective of whether or not the patients had diabetes.
CONCLUSIONS
We conclude that hyperglycemia in the acute phase of stroke cannot be explained by increased stress.
背景与目的
卒中急性期高血糖与预后不良相关。非糖尿病性卒中患者的高血糖是否由应激引起存在争议。
方法
我们研究了91例症状发作后24小时内入院的急性卒中连续患者的血糖水平和糖化血红蛋白。在27例未做选择的患者中，我们还在发病后第1天和第3天测量了儿茶酚胺。
结果
39例（43%）患者发现有高血糖，其中55%患有糖尿病或潜伏性糖尿病；其他患者为特发性高血糖。去甲肾上腺素水平与卒中严重程度相关（P = .005），与高血压相关（P = .03），但与血糖水平无关，无论患者是否患有糖尿病。
结论
我们得出结论，卒中急性期的高血糖不能用应激增加来解释。
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