Perelson A S, Bell G I
Nature. 1977 Jan 27;265(5592):304-10. doi: 10.1038/265304a0.
Mathematical models of homologous but unequal crossing over between sister chromatids are presented. For mispairing by one repeat, the evolution of a multigene family by unequal crossing over can be represented by a linear birth-death process. The fixation rate of one repeat in a multigene family is estimated. For mispairing by more than one repeat, some approximate results are obtained.
本文提出了姐妹染色单体之间同源但不等交换的数学模型。对于由一个重复序列引起的错配,多基因家族通过不等交换的进化可以用线性生死过程来表示。估计了多基因家族中一个重复序列的固定率。对于由多个重复序列引起的错配,得到了一些近似结果。