控制多基因家族大小的进化力量的计算机模拟。

A computer simulation of evolutionary forces controlling the size of a multigene family.

作者信息

Hood J M, Huang H V, Hood L

出版信息

J Mol Evol. 1980 Jul;15(3):181-96. doi: 10.1007/BF01732947.

Abstract

A Monte Carlo-type simulation of the evolution of a multigene family was performed. The model was designed to study the selective forces which may control the size of a multigene family. As expected, we find that direct selection on the size of the multigene family can control its size. More important, we find that selection acting upon the family as a single functional unit, in conjunction with homologous but unequal crossing over, can also control the size of a multigene family.

摘要

进行了一个多基因家族进化的蒙特卡洛类型模拟。该模型旨在研究可能控制多基因家族大小的选择力。正如预期的那样，我们发现对多基因家族大小的直接选择可以控制其大小。更重要的是，我们发现作用于该家族作为单个功能单元的选择，与同源但不等交换相结合，也可以控制多基因家族的大小。