Mahar P S, Nwokora G E
Armed Forces Hospital, Tabuk, Saudi Arabia.
Br J Ophthalmol. 1993 Jul;77(7):433-5. doi: 10.1136/bjo.77.7.433.
Mitomycin C in the form of eye drops in a concentration of 0.4 mg/ml (0.04%) was used as adjunctive treatment for primary and recurrent pterygium after surgical excision. The study was concurrent in nature and consisted of 32 pterygia in 30 patients and was done over a period of 36 months. The object was to observe the effect of mitomycin C drops on pterygium recurrence after surgical excision. Fifteen eyes of 15 patients were treated with 'bare sclera technique' for pterygium excision. Nine patients showed recurrence occurring within first 6 months of surgery. On the other hand 17 eyes of 15 patients after bare sclera pterygium excision received mitomycin 0.4 mg/ml (0.04%) eye drops four times a day for 2 weeks from first postoperative day. There was no recurrence of pterygium in this group. Follow up time for these cases ranged from 13-19 months.
浓度为0.4毫克/毫升（0.04%）的丝裂霉素C眼药水被用作原发性和复发性翼状胬肉手术切除后的辅助治疗。该研究为同期性研究，纳入了30例患者的32只翼状胬肉，研究历时36个月。目的是观察丝裂霉素C眼药水对手术切除后翼状胬肉复发的影响。15例患者的15只眼睛采用“单纯巩膜技术”进行翼状胬肉切除。9例患者在术后头6个月内出现复发。另一方面，15例患者的17只眼睛在单纯巩膜翼状胬肉切除术后，从术后第一天开始每天使用4次浓度为0.4毫克/毫升（0.04%）的丝裂霉素眼药水，持续2周。该组无翼状胬肉复发。这些病例的随访时间为13 - 19个月。
