Kondo Aki, Mimura Tatsuya, Goto Mari, Kamei Yuko, Yusuke Saito, Okuma Hiroko, Matsubara Masao
Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.
Open Ophthalmol J. 2017 Mar 31;11:47-50. doi: 10.2174/1874364101711010047. eCollection 2017.
To report a case of corneoscleral melt that occurred 50 years after resection of pterygium with postoperative administration of mitomycin C (MMC).
A 93-year-old woman developed acute corneal perforation and scleral melt in her left eye at 50 years after pterygium surgery with postoperative topical MMC. She underwent limbal transplantation. The anterior chamber reformed postoperatively and her intraocular pressure was normal. At 12 months after transplantation, best-corrected visual acuity was 20/500 and the graft-host junction was well apposed.
This case shows that corneoscleral melt can occur even 50 years after resection of pterygium combined with postoperative topical MMC.
报告1例翼状胬肉切除术后局部应用丝裂霉素C（MMC）50年后发生角巩膜融解的病例。
一名93岁女性在翼状胬肉手术后局部应用MMC 50年后，左眼发生急性角膜穿孔和巩膜融解。她接受了角膜缘移植术。术后前房形成，眼压正常。移植后12个月，最佳矫正视力为20/500，植片与宿主交界处贴合良好。
该病例表明，翼状胬肉切除联合术后局部应用MMC，即使在50年后仍可能发生角巩膜融解。
