1-氨基-4-苯基双环(2,2,2)辛烷（EXP 561）对大鼠脑和心脏中单胺摄取的阻断作用。 - Suppr | 超能文献

Blockade of monoamine uptake by 1-amino-4-phenylbicyclo(2,2,2)octane (EXP 561) in rat brain and heart.

作者信息

Wong D T, Molloy B B, Bymaster F P

出版信息

Neuropharmacology. 1977 Jan;16(1):11-5. doi: 10.1016/0028-3908(77)90040-5.

DOI:10.1016/0028-3908(77)90040-5

Abstract

摘要

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1

Blockade of monoamine uptake by 1-amino-4-phenylbicyclo(2,2,2)octane (EXP 561) in rat brain and heart.1-氨基-4-苯基双环(2,2,2)辛烷（EXP 561）对大鼠脑和心脏中单胺摄取的阻断作用。

Neuropharmacology. 1977 Jan;16(1):11-5. doi: 10.1016/0028-3908(77)90040-5.

2

In vitro studies on the inhibition of monoamine uptake by Org 6582 [proceedings].关于Org 6582对单胺摄取抑制作用的体外研究[会议论文集]

Br J Pharmacol. 1977 Mar;59(3):481P-482P.

3

The inhibition of monoamine uptake into rat brain synaptosomess by selected bicyclo-octanes and an analogous bicyclo-octene.特定双环辛烷及类似双环辛烯对大鼠脑突触体中单胺摄取的抑制作用

Biochem Pharmacol. 1978;27(24):2907-9. doi: 10.1016/0006-2952(78)90207-1.

4

Inhibition of amine uptake by 4-phenyl-bicyclo(2,2,2)octan-1-amine hydrochloride monohydrate (EXP 561) in rats.盐酸4-苯基双环(2,2,2)辛烷-1-胺一水合物（EXP 561）对大鼠胺摄取的抑制作用

Biochem Pharmacol. 1976 Nov 1;25(21):2409-10. doi: 10.1016/0006-2952(76)90039-3.

5

Effects of ORG 6582 on monoamine uptake in vitro.

Biochem Pharmacol. 1978 Apr 1;27(7):1023-7. doi: 10.1016/0006-2952(78)90152-1.

6

Effects of pre- and post-treatment with EXP 561 on the amine-depleting effects of p-chloroamphetamine and 6-hydroxydopamine in rats.EXP 561 预处理和后处理对大鼠中对氯苯丙胺和 6-羟基多巴胺的胺耗竭作用的影响。

Res Commun Chem Pathol Pharmacol. 1978 Sep;21(3):457-65.

7

Studies on 4-(p-bromophenyl)-bicyclo (2,2,2) octan-1-amine as an inhibitor of uptake into serotonin neurones.4-（对溴苯基）-双环（2,2,2）辛烷-1-胺作为血清素神经元摄取抑制剂的研究。

Neuropharmacology. 1978 Oct;17(10):815-8. doi: 10.1016/0028-3908(78)90069-2.

8

Proceedings: The selective inhibition of 5-hydroxy-tryptamine re-uptake by Org 6582.研究进展：Org 6582对5-羟色胺再摄取的选择性抑制作用

Br J Pharmacol. 1976 Mar;56(3):367P-368P.

9

Effects of Org 6582, chlorimipramine and desmethylimipramine on the depletion of biogenic amines from the rat brain in vivo.Org 6582、氯米帕明和去甲氯米帕明对大鼠脑内生物胺在体耗竭的影响。

Biochem Pharmacol. 1977 Jun 1;26(11):1083-4. doi: 10.1016/0006-2952(77)90248-9.

10

An inhibitor of dopamine uptake, LR5182, cis-3-(3,4-dichlorophenyl)-2-n,n-dimethylaminomethyl-bicyclo-[2,2,2]-octane, hydrochloride.一种多巴胺摄取抑制剂，LR5182，顺式-3-(3,4-二氯苯基)-2-N,N-二甲基氨基甲基-双环-[2,2,2]-辛烷，盐酸盐。

Life Sci. 1978 Sep 11;23(10):1041-7. doi: 10.1016/0024-3205(78)90664-1.

引用本文的文献

1

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.帕金森病诱导神经毒素，N-甲基-4-苯基-1,2,3,6-四氢吡啶：多巴胺能神经元对代谢产物N-甲基-4-苯基吡啶的摄取解释了其选择性毒性。

Proc Natl Acad Sci U S A. 1985 Apr;82(7):2173-7. doi: 10.1073/pnas.82.7.2173.

2

Pharmacological properties of EXP 561, a potential antidepressant drug.潜在抗抑郁药物EXP 561的药理学特性

J Neural Transm. 1987;70(1-2):81-97. doi: 10.1007/BF01252511.