He H
Second Affiliated Hospital, Hunan Hengyang Medical College.
Zhonghua Fu Chan Ke Za Zhi. 1993 Feb;28(2):82-4, 122-3.
Fourteen infertile women and two women with recurrent abortions were suspected of having luteal phase defect (LPD) by BBT charts. In these patients, the midluteal phase serum progesterone (P) levels were determined together with histological examination by the late luteal endometrial biopsies during the same cycle. The diagnostic criteria for LPD was BBT of luteal phase < or = eleven days, mean P level of 3 blood samples taken on three days during midluteal phase was less than 48 nmol/L (15 ng/ml) and the histological dating of endometrium was two or more days behind. The results showed that histological abnormality and low P level were 6.3% and 31.3%, respectively. When histological abnormality combined with lowered P level at the same cycle, the diagnosis of LPD increased to 87.5%. The author suggests that both midluteal phase P level and late luteal endometrial histological examination should be assessed at the same cycle in the diagnosis of LPD. BBT should also be assessed.
通过基础体温（BBT）图表，14名不孕女性和2名反复流产的女性被怀疑患有黄体期缺陷（LPD）。在这些患者中，在同一周期内，通过黄体晚期子宫内膜活检进行组织学检查的同时，测定黄体中期血清孕酮（P）水平。LPD的诊断标准为：黄体期BBT≤11天，黄体中期三天采集的3份血样的平均P水平低于48 nmol/L（15 ng/ml），且子宫内膜组织学分期落后两天或更多。结果显示，组织学异常和低P水平分别为6.3%和31.3%。当同一周期组织学异常与P水平降低同时出现时，LPD的诊断率增至87.5%。作者建议，在LPD的诊断中，应在同一周期评估黄体中期P水平和黄体晚期子宫内膜组织学检查。基础体温也应进行评估。
