Lu S M, Shi Y F
Obstetric and Gynecologic Hospital, Zhejiang Medical University, Hangzhou.
Zhonghua Fu Chan Ke Za Zhi. 1993 Feb;28(2):85-7, 123.
The production of tumor necrosis factor (TNF) induced by LPS in the peripheral blood mononuclear cells from the patients with malignant and benign ovarian tumors were determined. Decreased production of TNF were observed in the patients with malignant ovarian tumor. In the advanced cases, TNF were lower than that in the early ones, which may indicate the progression of the tumors. These findings suggested that the TNF may be a useful indicator to diagnose the malignant tumors and prognosticate the tumors' developing.
测定了恶性和良性卵巢肿瘤患者外周血单核细胞中脂多糖诱导的肿瘤坏死因子（TNF）的产生。在恶性卵巢肿瘤患者中观察到TNF产生减少。在晚期病例中，TNF低于早期病例，这可能表明肿瘤进展。这些发现提示TNF可能是诊断恶性肿瘤和预测肿瘤发展的有用指标。
