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一项基于医院的关于使用辅助医疗人员进行宫颈癌临床降期的研究。

A hospital-based study on the use of paramedical personnel for clinical downstaging of cancer cervix.

作者信息

Bhargava V L, Verma K, Sharma R, Batra S, Anandalakshmy P N

机构信息

Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, New Delhi.

出版信息

Indian J Med Res. 1993 Apr;98:65-8.

PMID:8344733
Abstract

Two auxiliary nurse midwives (ANMs) were recruited and trained to recognize normal and different types of abnormal cervices. A total of 2102 women were examined by a gynaecologist and ANM independently and their findings were noted. Comparison of their findings showed an overall agreement of 89.6 per cent (Kappa 0.84 with standard error of 0.015 and a significantly large Z value of 55.6). Gross examination of 4679 women attending the Gynaecology OPD revealed normal cervix in 49.6 per cent and suspected lesions or malignant cervix in 3.4 per cent of women. Cytology smears were taken in 3608 women. Adequacy of smears was 97 per cent. Comparing the group clinically diagnosed as highly suspected or malignant to the cytologically diagnosed suspected group (atypical and malignant), clinical examination had a sensitivity of 81.7 per cent and specificity of 97.3 per cent; while comparison of the group clinically diagnosed as abnormal cervix to abnormal cytology (all grades of dysplasia, atypical and malignant cells), the clinical examination had a sensitivity of 92.5 per cent and specificity of 37.4 per cent. It was concluded that paramedical staff (ANMs) can be relied upon to do speculum examination in women in the community and take cytology smears in selected cases.

摘要

招募并培训了两名助理护士助产士(ANM),使其能够识别正常宫颈和不同类型的异常宫颈。共有2102名女性分别由一名妇科医生和助理护士助产士进行检查,并记录她们的检查结果。对他们检查结果的比较显示总体一致性为89.6%(Kappa值为0.84,标准误差为0.015,Z值显著大,为55.6)。对4679名到妇科门诊就诊的女性进行大体检查发现,49.6%的女性宫颈正常,3.4%的女性宫颈有可疑病变或恶性病变。对3608名女性进行了细胞学涂片检查。涂片的充分率为97%。将临床诊断为高度可疑或恶性的组与细胞学诊断为可疑的组(非典型和恶性)进行比较,临床检查的敏感性为81.7%,特异性为97.3%;而将临床诊断为宫颈异常的组与异常细胞学(所有级别的发育异常、非典型和恶性细胞)进行比较,临床检查的敏感性为92.5%,特异性为37.4%。得出的结论是,辅助医务人员(助理护士助产士)可以在社区女性中进行窥器检查,并在选定病例中采集细胞学涂片。

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