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古代欧洲人的临床耳硬化症和外耳道骨瘤(立陶宛古骨学样本研究)

Clinical otosclerosis and auditory exostoses in ancient Europeans (investigation of Lithuanian paleoosteological samples).

作者信息

Sakalinskas V, Jankauskas R

机构信息

Clinic of Otorhinolaryngology, Faculty of Medicine, University of Vilnius, Lithuania.

出版信息

J Laryngol Otol. 1993 Jun;107(6):489-91. doi: 10.1017/s0022215100123540.

DOI:10.1017/s0022215100123540
PMID:8345295
Abstract

The purpose of this investigation was to establish the incidence of clinical otosclerosis and auditory exostoses in Lithuanian paleopopulations. The total sample consists of 4080 skulls, dating from the Neolithic to the C17th-C18th A.D., investigated visually, under magnification and radiologically. Eight cases of clinical otosclerosis and 22 of auditory exostoses were identified. The general epidemiology of otosclerosis (0.19 +/- 0.08 per cent) was established to be similar to contemporary populations. This suggests that there are no new aetiological factors attributable to our modern society. Clear diminution of the incidence of auditory exostoses from the 1st to the 2nd millenium A.D. (3.46 +/- 0.76 per cent, against 0.06 +/- 0.04 per cent, p < 0.001) and definite sexual differences (males: 1.21 +/- 0.28 per cent; females: 0.17 +/- 0.10 per cent, p < 0.001) were also noted. In general, auditory exostoses were found much more frequently than in recent populations.

摘要

本次调查的目的是确定立陶宛古代人群中临床耳硬化症和听骨外生骨疣的发病率。总样本包括4080个头骨,年代从新石器时代到公元17至18世纪,通过肉眼、放大观察及放射学方法进行研究。共发现8例临床耳硬化症和22例听骨外生骨疣。耳硬化症的总体流行病学情况(0.19±0.08%)被确定与当代人群相似。这表明不存在归因于现代社会的新病因。同时还注意到,从公元1千年到2千年,听骨外生骨疣的发病率明显降低(分别为3.46±0.76%和0.06±0.04%,p<0.001),且存在明确的性别差异(男性:1.21±0.28%;女性:0.17±0.10%,p<0.001)。总体而言,听骨外生骨疣的发现频率比近代人群高得多。

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