Okazaki T, Kiyokawa K, Arakawa H, Kadohno N, Katano M, Kanno T
1st Department of Mitsubishi Yuka Bio-Clinical Laboratories, Inc., Tokyo.
Rinsho Byori. 1993 Mar;41(3):298-302.
We could observe several anomalous electrophoretic patterns of haptoglobin during serotype analysis. We classified these anomalous patterns of haptoglobin into two major classes. The first is the change of number of haptoglobin bands, and the second is the shift from the normal serotype patterns. The change of number of haptoglobin bands was caused by unsaturation of haptoglobin in binding with hemoglobin, mixing of different serotypes by blood transfusion or injection of haptoglobin and serotype variants of haptoglobin. The shift of haptoglobin PAGE pattern was occurred from a large amount of M-protein or lipoproteins in serum.
在血清型分析过程中，我们能够观察到触珠蛋白的几种异常电泳图谱。我们将这些触珠蛋白的异常图谱分为两大类。第一类是触珠蛋白条带数量的变化，第二类是与正常血清型图谱的偏移。触珠蛋白条带数量的变化是由触珠蛋白与血红蛋白结合不饱和、输血或注射触珠蛋白导致不同血清型混合以及触珠蛋白的血清型变异引起的。触珠蛋白PAGE图谱的偏移是由血清中大量的M蛋白或脂蛋白导致的。
