Yehuda R, Resnick H, Kahana B, Giller E L
Department of Psychiatry, Mount Sinai School of Medicine, New York.
Psychosom Med. 1993 May-Jun;55(3):287-97. doi: 10.1097/00006842-199305000-00006.
The biological consequences of stress have been studied for over half a decade, however, little is known about persistent biological alterations after extreme stress in humans. Posttraumatic stress disorder (PTSD) is a syndrome that occurs in some individuals after exposure to extreme stress. In this review, we summarize some of our studies of hypothalamic-pituitary-adrenal axis alterations in PTSD and compare and contrast these findings with knowledge concerning biological changes following stress.
