• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[一种用于实验室的新型生物辐照器]

[A new biological irradiator for the laboratory].

作者信息

Tosi G, Brambilla M G, Invernizzi S, Leone R, Pertosa M

机构信息

Servizio di Fisica Sanitaria, Ospedale Niguarda Ca' Granda, Milano.

出版信息

Radiol Med. 1993 Jul-Aug;86(1-2):127-34.

PMID:8346343
Abstract

The use of high doses (15-20 Gy) of X- or gamma-rays to irradiate blood-derived materials is a common practice by now. It is usual especially when materials must be transfused into non-immunocompetent patients. This is done to avoid the so-called GVH disease. Nowadays, for this purpose, units containing radioactive gamma-emitting sources with high activity and long half-life (usually 137Cs) are on the market. The characteristics of these "irradiators" allow their implementation in any laboratory with no need of structural shieldings. In spite of it, serious accidents (e.g., fire, fallings, etc.) which could imply hazards for the operating staff and even the general population, cannot be excluded. At the same time, the problem of long-term disposal of exhausted sources cannot be neglected. For these reasons, a new type of self-shielded irradiator was designed. It is equipped with an X-ray tube, operating at nearly 200-kV voltage, with 12-mA anodic current. The system is water- and oil-cooled and can work for a long time without thermal overloads. In this paper, the environmental and dosimetric measurements for beam characterization are reported. The system can produce beams with satisfactory characteristics for this specific problem. Moreover, its use may greatly reduce administrative radioprotection problems.

摘要

目前,使用高剂量(15 - 20戈瑞)的X射线或γ射线辐照血液衍生材料是一种常见做法。特别是在材料必须输注给免疫功能不全患者时,这种做法很普遍。这样做是为了避免所谓的移植物抗宿主病。如今,为此目的,市场上有含有高活性和长半衰期(通常为137铯)的放射性γ发射源的装置。这些“辐照器”的特性使其无需结构屏蔽就能在任何实验室中使用。尽管如此,仍不能排除可能对操作人员甚至普通民众构成危害的严重事故(例如火灾、掉落等)。同时,废弃源的长期处置问题也不能忽视。出于这些原因,设计了一种新型的自屏蔽辐照器。它配备了一个X射线管,工作电压接近200千伏,阳极电流为12毫安。该系统采用水冷却和油冷却,可长时间工作而不会出现热过载。本文报道了用于束流特性表征的环境和剂量测量。该系统能够产生针对这一特定问题具有令人满意特性的束流。此外,其使用可大大减少管理上的辐射防护问题。

相似文献

1
[A new biological irradiator for the laboratory].[一种用于实验室的新型生物辐照器]
Radiol Med. 1993 Jul-Aug;86(1-2):127-34.
2
Replacement of 137Cs irradiators with x-ray irradiators.用X射线辐照器替代137铯辐照器。
Health Phys. 2009 Feb;96(2 Suppl):S27-30. doi: 10.1097/01.HP.0000334555.78657.bc.
3
Deciding between an X-Ray and 137Cs Irradiator - It's not just about Energy Spectra.在 X 射线和 137Cs 辐照器之间做出选择——不仅仅是能量谱的问题。
Radiat Res. 2019 Nov;192(5):493-506. doi: 10.1667/RR15395.1. Epub 2019 Sep 10.
4
University of California Replacement of Cesium Irradiators with Alternative Technologies.加州大学用替代技术替代铯辐照器。
Health Phys. 2020 Feb;118(2):209-214. doi: 10.1097/HP.0000000000001160.
5
Successful Migration from Radioactive Irradiators to X-ray Irradiators in One of the Largest Medical Centers in the US.美国最大医疗中心之一成功将放射性辐照源迁移至 X 射线辐照源。
Health Phys. 2019 Nov;117(5):558-570. doi: 10.1097/HP.0000000000001095.
6
[Classification of laser irradiation and safety measures].[激光照射的分类及安全措施]
Med Pregl. 1998 Sep-Oct;51(9-10):415-8.
7
Dose characterization of the rad source 2400 X-ray irradiator for oyster pasteurization.用于牡蛎巴氏杀菌的2400型X射线辐照器辐射源的剂量特性
Appl Radiat Isot. 2009 Feb;67(2):334-9. doi: 10.1016/j.apradiso.2008.10.013. Epub 2008 Nov 5.
8
Comparison of X-ray vs. gamma irradiation of CPDA-1 red cells.CPDA-1红细胞的X射线与γ射线辐照比较。
Vox Sang. 2005 Nov;89(4):215-9. doi: 10.1111/j.1423-0410.2005.00699.x.
9
Air kerma rate constants for gamma emitters used most often in practice.实际应用中最常用的γ射线发射体的空气比释动能率常数。
Radiat Prot Dosimetry. 2005;115(1-4):247-50. doi: 10.1093/rpd/nci131.
10
Calibration of a 137Cs gamma-ray beam irradiator using large size chambers.使用大尺寸电离室对¹³⁷Csγ射线束辐照器进行校准。
Appl Radiat Isot. 2007 Apr;65(4):401-6. doi: 10.1016/j.apradiso.2006.10.008. Epub 2006 Nov 22.