Takac S, Stojanović S
Zavod za sudsku medicinu, Medicinski fakultet, Novi Sad.
Med Pregl. 1998 Sep-Oct;51(9-10):415-8.
The use of lasers in medicine and especially surgery is rapidly expanding in many disciplines from clinical laboratory to the office practice and operating room. It is essential that users of this powerful tool have knowledge of their potential hazards and the measures to protect patients and personnel against injuries or undesired effects. Below, we have included information about the way lasers are classified; the development of protective standards; the current status of protection standards that apply to lasers, especially those used in medicine/surgery; the specific kinds of hazards associated with medical/surgical applications; and the measures by which hazards have been controlled. Since laser technology is still a young field, it is likely that problems unknown at present will occur and methodologies for controlling hazards will evolve. The American National Standards Committee produced the first consensus standard Z136.1 in 1973. The Standard was revised in 1976 to accommodate differences in biological effects for different wavelengths in the visible spectrum. The ANSI Standard has been revised again in 1980, and currently (1984) there are two additional standards in preparation, Z136.2 and 136.3, which treat the safe use of light-emitting diodes and the safe use of lasers in the health care environment, respectively. Most surgical and medical lasers are Class III or IV. Some lasers have a Class IV therapy level beam plus a Class I or II alignment beam. When using lasers, it is possible to generate incandescence or fluorescence in an irradiated object. This can occur even with protective eyewear, because the correlated radiations are usually of a different wavelength. Generally, this should not be a problem when beams are directed at biological material. However, hazard could be caused by lasers designed to produce fluorescence. Control of correlative radiation in a laser system is required in the federal regulations. Hazards of lasers may be grouped as those to the eye, skin and associated hazards, fire, x-rays, electrical, fumes, toxic materials, etc. Effects on tissue are governed by the following factors:--the energy or power density of the beam;--the absorption in tissue at the laser wavelength;--the time the beam is held at a given area.;--the protective effects of heat removal by thermal conduction and by circulation. Eye hazards include thermal burns or acoustical disruption (shock waves) from high-powered or high-energy beams in the visible and near infrared wavelengths. Direct beam exposure or specular or diffuse reflaction from these very high-power lasers can also cause injuries to other parts of the retina. For example, beams can directly penetrate through the sclera and cause retinal injury. Near ultraviolet (less than 400 hm) and far infrared (.3000 hm including CO2 lasers) can cause moderate to severe corneal burns. Far ultraviolet (200-315 nm), mid infrared (1400-3000 nanometers) can cause welders' flash or snow blindness and chronic exposure could cause cataract, and exposure to ultraviolet rays may be carcinogenic. For CO2 lasers, the far infrared radiation is attenuated by plastic goggles, or by glasses, or quartz. Other eyewear with special filters is used for different lasers. The whole personnel who may be exposed to direct beams, specular reflections, and many times diffuse reflections must wear protective eyewear. In all cases the surgeon and others viewing the procedure through the endoscope need glasses or suitable protective lenses installed in the endoscope. Persons who are not viewing the beam may not need to wear protective glasses with the same level of optical density. Glasses may be selected to provide protection for lasers operating in the visible wavelength to the point where the normal aversion response could protect the individual.
激光在医学尤其是外科手术中的应用正在许多领域迅速扩展,从临床实验室到门诊实践以及手术室。至关重要的是,这种强大工具的使用者要了解其潜在危害以及保护患者和工作人员免受伤害或不良影响的措施。以下,我们纳入了有关激光分类方式、防护标准的发展、适用于激光尤其是医学/外科手术中使用的激光的防护标准现状、与医学/外科应用相关的具体危害种类以及已控制危害的措施等信息。由于激光技术仍是一个新兴领域,很可能会出现目前未知的问题,并且控制危害的方法也会不断演变。美国国家标准委员会于1973年制定了首个共识标准Z136.1。该标准于1976年修订,以适应可见光谱中不同波长生物效应的差异。美国国家标准学会(ANSI)标准于1980年再次修订,目前(1984年)还有另外两项标准正在制定中,即Z136.2和136.3,分别涉及发光二极管的安全使用以及医疗环境中激光的安全使用。大多数外科和医用激光属于III类或IV类。一些激光具有IV类治疗级光束以及I类或II类准直光束。使用激光时,有可能在被照射物体中产生炽热或荧光。即使佩戴防护眼镜也可能发生这种情况,因为相关辐射通常具有不同波长。一般来说,当光束照射生物材料时这不应该是个问题。然而,旨在产生荧光的激光可能会造成危害。联邦法规要求控制激光系统中的相关辐射。激光的危害可分为对眼睛、皮肤及相关危害、火灾、X射线、电气、烟雾、有毒物质等。对组织的影响取决于以下因素:——光束的能量或功率密度;——激光波长下组织中的吸收情况;——光束在给定区域停留的时间;——通过热传导和循环散热的保护作用。眼睛危害包括可见和近红外波长的高功率或高能量光束造成的热灼伤或声学破坏(冲击波)。这些高功率激光的直接光束照射或镜面反射或漫反射也可能对视网膜的其他部位造成损伤。例如,光束可直接穿透巩膜并导致视网膜损伤。近紫外线(小于400纳米)和远红外线(大于3000纳米,包括二氧化碳激光)可导致中度至重度角膜灼伤。远紫外线(200 - 315纳米)、中红外线(1400 - 3000纳米)可导致焊工闪光或雪盲,长期暴露可能导致白内障,并且紫外线暴露可能具有致癌性。对于二氧化碳激光,远红外辐射可被塑料护目镜、眼镜或石英衰减。其他带有特殊滤光片的眼镜用于不同的激光。所有可能暴露于直接光束、镜面反射以及多次漫反射的人员都必须佩戴防护眼镜。在所有情况下,外科医生和通过内窥镜观看手术过程的其他人需要佩戴眼镜或在内窥镜中安装合适的防护镜片。不观看光束的人员可能不需要佩戴具有相同光密度水平的防护眼镜。可以选择眼镜为在可见波长下操作的激光提供保护,直至正常的躲避反应能够保护个人的程度。