Wüthrich R, Hold G, Bannwart F, Imhof E
Medizinische Klinik, Stadtspital Triemli, Zürich.
Schweiz Rundsch Med Prax. 1993 Jul 6;82(27-28):769-73.
This 49-year-old man with the acquired immunodeficiency syndrome (AIDS) was admitted to the hospital because of fever, weight loss and respiratory symptoms. The radiograph of the chest showed diffuse fine nodular opacities. Histology of lung and lymph node revealed a necrotising granulomatosis and yeasts suggesting histoplasmosis. It's identity was confirmed by positive cultures for Histoplasma capsulatum in blood, urine, lung specimen and lymph node. There was a successful induction treatment and a maintenance therapy with amphotericin B. We discuss disseminated histoplasmosis in the immunodeficiency syndrome.
这位49岁的获得性免疫缺陷综合征（艾滋病）患者因发热、体重减轻和呼吸道症状入院。胸部X光片显示弥漫性细小结节状阴影。肺和淋巴结组织学检查显示坏死性肉芽肿病和酵母，提示组织胞浆菌病。血液、尿液、肺标本和淋巴结中荚膜组织胞浆菌培养阳性，证实了其诊断。采用两性霉素B进行了成功的诱导治疗和维持治疗。我们讨论免疫缺陷综合征中的播散性组织胞浆菌病。
