Vantilcke Vincent, Boukhari Rachida, Jolivet Anne, Vautrin Cyrille, Misslin Caroline, Adenis Antoine, Nacher Mathieu
Centre hospitalier de l'ouest Guyanais, service de médecine, Saint Laurent du Maroni, French Guiana.
Centre hospitalier de l'ouest Guyanais, Laboratoire Polyvalent, Saint Laurent du Maroni, French Guiana.
Int J STD AIDS. 2014 Aug;25(9):656-61. doi: 10.1177/0956462413516299. Epub 2014 Mar 4.
In Western French Guiana, there was a dramatic increase in HIV prevalence between 1990 and 2000. The present study describes the causes of fever among HIV patients hospitalized in the medical ward of the only hospital in the western part of French Guiana. A retrospective descriptive study was conducted between 1 January 2008 and 30 June 2010 in the department of medicine of Saint Laurent du Maroni Hospital. The main characteristics of 67 patients having presented with fever in the first 48 hours of hospitalization were described. Among patients with CD4 <200/mm(3)the main febrile opportunistic infection was disseminated histoplasmosis (41.1%). Among patients with CD4 counts <50/mm(3)and fever without focal points 85.7% had disseminated histoplasmosis. Three patients died and all had disseminated histoplasmosis. Disseminated histoplasmosis is the most common febrile opportunistic infection in western French Guiana. Primary prophylaxis with itraconazole among immunocompromised patients seems warranted.
在法属圭亚那西部，1990年至2000年间艾滋病毒感染率急剧上升。本研究描述了在法属圭亚那西部唯一一家医院内科病房住院的艾滋病毒患者发热的原因。2008年1月1日至2010年6月30日期间，在圣洛朗迪马罗尼医院内科进行了一项回顾性描述性研究。描述了67例在住院头48小时内出现发热的患者的主要特征。在CD4<200/mm³的患者中，主要的发热性机会性感染是播散性组织胞浆菌病（41.1%）。在CD4计数<50/mm³且无局灶性病变发热的患者中，85.7%患有播散性组织胞浆菌病。3例患者死亡，均患有播散性组织胞浆菌病。播散性组织胞浆菌病是法属圭亚那西部最常见的发热性机会性感染。对免疫功能低下的患者进行伊曲康唑的一级预防似乎是必要的。
