Fernández-Trigo V, Sugarbaker P H
Cancer Institute, Washington Hospital Center, Washington, DC.
Tumori. 1993 Apr 30;79(2):77-91. doi: 10.1177/030089169307900201.
The principles of management of all sarcomas that involve the abdominal and pelvic cavity are presented. The anatomic sites for the primary malignancy include retroperitoneal sarcomas, pelvic side-wall sarcomas, sarcomas arising from the abdominal viscera, and sarcomas arising from the pelvic organs. All histologic types of sarcomas may be considered together when therapeutic options are being discussed. This presentation stresses surgical removal with an adequate margin of resection as the principal goal of management. The curative treatment of these cancers places great emphasis on the surgeon's knowledge of anatomy, technical skills, innovation, and surgical courage. Systemic chemotherapy and radiotherapy have not shown reproducible efficacy. Complete resection in the absence of tumor spillage remains the only reliable treatment option. Possible benefits of induction chemotherapy and intraperitoneal chemotherapy using cisplatin and doxorubicin in the early postoperative period are presented.
本文介绍了所有累及腹腔和盆腔的肉瘤的管理原则。原发性恶性肿瘤的解剖部位包括腹膜后肉瘤、盆腔侧壁肉瘤、起源于腹部内脏的肉瘤以及起源于盆腔器官的肉瘤。在讨论治疗方案时，可将所有组织学类型的肉瘤一并考虑。本报告强调以足够的切除 margins 进行手术切除作为管理的主要目标。这些癌症的根治性治疗非常重视外科医生的解剖学知识、技术技能、创新能力和手术勇气。全身化疗和放疗尚未显示出可重复的疗效。在无肿瘤溢出的情况下进行完全切除仍然是唯一可靠的治疗选择。还介绍了术后早期使用顺铂和阿霉素进行诱导化疗和腹腔内化疗可能带来的益处。 （注：原文中“margin of resection”直译为“切除边缘”，这里根据语境意译为“切除 margins”，可能是因为专业术语的习惯用法，不太确定具体所指，你可根据实际专业知识调整。）
