Woodward E R
Postgrad Med. 1977 Feb;61(2):143-50. doi: 10.1080/00325481.1977.11712121.
Surgical intervention is usually indicated in reflux esophagitis when medical therapy fails to control symptoms. Since most patients with peptic esophagitis also have a sliding hiatal hernia, early procedures focused on hernia repair. Weakness of the lower esophageal sphincter is now known to be the pathogenetic mechanism, and Belsey, Nissen, and Hill have developed operations to restore sphincteric function. The Hill repair is used most often because of its low incidence of side effects, but the other procedures are recommended in specific situations. Stricture, the most common complication of reflux esophagitis, presents a special problem in treatment because interference with swallowing is added to the characteristic symptoms of reflux. Because of its high long-term success rate, the combined Thal-Nissen procedure is preferred to forceful dilation plus an antireflux operation.
当药物治疗无法控制反流性食管炎的症状时,通常需要进行手术干预。由于大多数消化性食管炎患者同时患有滑动性食管裂孔疝,早期手术主要侧重于疝修补。现在已知食管下括约肌功能减弱是其发病机制,贝尔西、尼森和希尔等人开发了恢复括约肌功能的手术。希尔修补术因其副作用发生率低而最常被使用,但在特定情况下也推荐其他手术。狭窄是反流性食管炎最常见的并发症,在治疗中是一个特殊问题,因为吞咽障碍叠加了反流的典型症状。由于其长期成功率高,与强力扩张加抗反流手术相比,联合塔尔-尼森手术更受青睐。